Can a 305 memcal be used for a 350 tune?

what I'm trying to say is a 305 swapped to a 350

I have a 305 memcal but have an adapterboard and a chip tuned for the 350?

does the memcal have to be a 350 one?

 

As far as I know the other chips besides the PROM on the MEMCAL control the limp-mode and the cylinder select.

The limp-mode may differ from 305 to 350, but that only comes into play if the PROM becomes non-functional. The cylinder select just tells the ECM how many cylinders the engine is, so no difference between 305 & 350 in this regard.

Also, I run a 305 PROM on a 350 memcal via an adapter board, and have not noticed any related issues in the limited amount of driving I have on the setup.

EDIT: Make sure to read utilityguy2's post below. The info I gave here is only valid for the '165 ECM. Sorry for any confusion.

 

If you are talking 1227165 MAF ECM and Memcal without the on board ESC knock filter, then yes it is as BlueIroc says. If it is a 90-92 SD 1227730 ECM Then the ESC knock filter on the Memcal and the knock sensors are different between the 5.0 and 5.7 engines and that would need to be addressed.