I have recently acquired a set of L98 injectors and i need some advise/opinions.

Would my car ran the same with 22lb injectors as compared to my current 19lb after i change the setting in the prom?

I am not really looking for any performance gain but as long as the car doesn't run worse..

 

You really won't see any performance gain. As you mentioned you will have to change the injector constant in the PROM. The benefit you will get is that if/when you mod the engine in the future you already have the ability to deliver more fuel.